Publications & Presentations

Flight Demonstration of a Laser Hygrometer Payload for the ScanEagle UAS

D. Sonnenfroh, S-J. Chen, and M. Zondlo
Paper A02107, Unmanned Systems in Atmospheric Research I
American Geophysical Union Fall Meeting (Virtual)
7 December, 2020

  • Detailed cloud macro and microphysical properties remain a challenging measurement goal.
  • Enhanced knowledge of these properties is needed to increase understanding of various cloud processes, including entrainment and droplet growth, that are important in both weather
…
forecasting and climate change.
  • Water vapor gradients affects droplet growth rates and, together with temperature, are needed for determination of supersaturation values.
  • High sensitivity, high accuracy measurements of water vapor and temperature are needed at high spatial resolution, and therefore at high measurement rate
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    Acknowledgement
    This material is based upon work supported by the U.S. Department of Energy, Office of Science, Office of DOE Chicago Ops, un de r Award Number(s) DE SC0015104.
    Disclaimer:
    This report was prepared as an account of work sponsored by an agency of the United States Government. Neither the United St ate s Government nor any agency thereof, nor any of their employees makes any warranty, express or implied, or assumes any legal liability or responsibility for the accuracy, completeness, or usefulness of any information , apparatus, product, or process disclosed, or represents that its use would not infringe privately owned rights.
    Reference herein to any specific commercial product, process, or service by trade name, trademark, manufacturer, or otherwise do es not necessarily constitute or imply its endorsement, recommendation, or favoring by the United States Government or any agency thereof. The views and opinions of authors expressed herein do not necessarily state or reflect tho se of the United States Government or any agency thereof.

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    Automated analysis of tissue heterogeneity based on OCT images for improving personalized cancer therapy effectiveness

    Mark Scimone, Gopi Maguluri, Jesung Park, Nicusor Iftimia
    SPIE, Photonics West,
    San Francisco, CA, February 4, 2020

    Optical coherence tomography enables high-resolution, nondestructive imaging up to 1 mm in depth.

    • Full 3D reconstructions allow for visualization of the full extent of tumor

    • Estimation of tumor content allows for spatial exclusion in important personalized cancer treatment assays.
    – Also useful for relevant 3D drug development assays

    © 2020 Physical Sciences Inc. All rights reserved. This work was sponsored by The National Cancer Institute under grant number 2R44CA173998-02A1 . The content is solely the responsibility of the authors and does not necessarily represent the official views of the National Institutes of Health. We are very grateful for this support.

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    A High Throughput Spectroscopic Dosimeter for Simultaneous Measurement of Singlet Oxygen and Photosensitizer during PDT Treatment

    Y. Zhao, T. Moritz, M. Hinds, J. Gunn, B. W. Pogue, and S. J. Davis
    SPIE Photonics West / BIOS Conference
    San Francisco, CA
    February 1, 2020
    SPIE Paper No. 11220-7

    Successful development of a singlet oxygen spectrometer applicable for PDT treatment using a cw laser

    Preliminary demonstration during in vivo animal experiments

    Continued animal study is ongoing.

    Next step will be to reduce the system cost and potentially include time gated measurement capability.

    © 2020 Physical Sciences Inc. All rights reserved. This work was sponsored by The National Cancer Institute under grant number 5R44CA213607 03. The content is solely the responsibility of the authors and does not necessarily represent the official views of the National Institutes of Health. We are very grateful for this support.

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    High Yield and Economical Production of Rare Earth Elements from Coal Ash

    Dorin V. Preda, Prakash B. Joshi, David P. Gamliel, Jeffrey Y. Yee, Russell D. Lambert, James C. Hower, John G. Groppo, Jr., Todd Beers, and Mike Schrock
    2019 International Pittsburgh Coal Conference
    Pittsburgh, PA
    September 3-6, 2019

    Rare Earth Elements (REE) in fossil fuel derived solids and liquids

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    Sensor Applications for DFB-ICLs and QCLs

    Mickey B. Frish
    LC Workshop
    October 28, 2019
    Princeton University, Princeton, NJ

    We have demonstrated laboratory feasibility of novel miniature sensor packaging, with integrated laser source, sensor element, and detector on a simple monolithic platforms

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    Synchronized, concurrent optical coherence tomography and videostroboscopy for monitoring vocal fold morphology and kinematics

    Synchronized, concurrent optical coherence tomography and videostroboscopy for monitoring vocal fold morphology and kinematics
    GOPI MAGULURI, DARYUSH MEHTA, JAMES KOBLER, JESUNG, PARK, AND NICUSOR IFTIMIA
    Biomedical Optics Express Vol. 10, Issue 9, pp. 4450-4461 (2019) • https://doi.org/10.1364/BOE.10.004450

    Voice disorders affect a large number of adults in the United States, and their clinical evaluation heavily relies on laryngeal videostroboscopy, which captures the mediallateral and anterior-posterior motion of the vocal folds using stroboscopic sampling.

    …
    However, videostroboscopy does not provide direct visualization of the superior-inferior movement of the vocal folds, which yields important clinical insight. In this paper, we present a novel technology that complements videostroboscopic findings by adding the ability to image the coronal plane and visualize the superior-inferior movement of the vocal folds. The technology is based on optical coherence tomography, which is combined with videostroboscopy within the same endoscopic probe to provide spatially and temporally co-registered images of the mucosal wave motion, as well as vocal folds subsurface morphology. We demonstrate the capability of the rigid endoscopic probe, in a benchtop setting, to characterize the complex movement and subsurface structure of the aerodynamically driven excised larynx models within the 50 to 200 Hz phonation range. Our preliminary results encourage future development of this technology with the goal of its use for in vivo laryngeal imaging.

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    © 2019 Optical Society of America under the terms of the OSA Open Access Publishing Agreement. Users may use, reuse, and build upon the article, or use the article for text or data mining, so long as such uses are for non-commercial purposes and appropriate attribution is maintained. All other rights are reserved.

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