Optical Coherence Tomography

Optical coherence tomography (OCT) is a non-invasive, low-coherence interferometric technique for generation of high-resolution, cross-sectional images and three-dimensional volumetric maps of biological samples and other specimen. Fourier domain OCT is a new, high speed version that allows video rate image acquisition and increased signal-to-noise ratio. PSI is using OCT technology in many medical fields, including for the investigation and diagnosis of retinal diseases, the detection of pancreatic, colon, breast, and prostrate cancer, and for the study of pharmacological agents that affect cardiac output in animal models. The multimodal image-guided systems we develop often combine OCT with another diagnostic or therapeutic modality.