Biomedical Imaging Group

Mission

The mission of the Biomedical Imaging group is to develop innovative biomedical optical systems for use by researchers, clinicians, and other medical personnel in the detection of diseases, the discovery of novel therapies, and greater understanding of the human body from system and organ to sub-cellular and molecular structures. We perform research and development in a wide variety of interdisciplinary programs for the NIH, DoD, and other government and commercial organizations. Some of our work is built on our core competencies in ophthalmology including the development of:

• A hand-held line scanning laser ophthalmoscope (LSLO)
• A tracking scanning laser ophthalmoscope (TSLO)
• A tracking optical coherence tomography (TOCT) imager
• A hybrid LSLO/spectral domain OCT imager
• An adaptive optics scanning laser ophthalmoscope (AOSLO)
• An adaptive optics spectral domain optical coherence tomographer (AO-SDOCT)
• Instrumentation and techniques for retinal hemodynamics
• An angiography/laser delivery system for automated photodynamic therapy of retinal diseases such as age-related macular degeneration
• Custom FPGA-based SDOCT processing board.

Ophthalmic imaging instruments developed by the Biomedical Imaging Group.

Our retinal tracking ocular interface is currently being sold to researchers interested in functional imaging, SLO, OCT, adaptive optics, multi-focal ERG, low vision studies, etc. We are also engaged in projects that use optics for imaging and therapies for other non-ophthalmic applications, including the development of:

• Full-field endoscopic optical coherence microscopy
• Fine needle aspiration biopsy for cancer screening of adipose tissues (e.g., breast)
• Zebrafish imaging for angiogenesis and drug discovery studies
• Polarization imaging of enzymatic activity
• OCT-guided laser ablation therapies for pancreatic cancer
• Advanced three-dimensional tracking systems
• Optical diffuse tomography for neuro-imaging
• Swept source Fourier domain OCT systems.

Area Leadership

Dr. Daniel Hammer

The Biomedical Imaging group is led by Dr. Daniel Hammer. Dr. Hammer has 15 years experience in the invention, design, development, and application of biomedical optics and instrumentation to a broad range of interdisciplinary research programs.

Daniel X. Hammer Physical Sciences Inc. 20 New England Business Center Andover, MA 01810-1077 Telephone: (978) 689-0003 Fax: (978) 689-3232 hammer@psicorp.com

Laser Sources and Applications Publications Laser Sources and Applications Presentations