Physical Sciences Inc. Publications Abstract: Adaptive optics scanning laser ophthalmoscope for stabilized retinal imaging

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Abstract: Adaptive optics scanning laser ophthalmoscope for stabilized retinal imaging

Daniel X. Hammer, R. Daniel Ferguson, Chad E. Bigelow, Nicusor V. Iftimia, Teoman E. Ustun, Stephen A. Burns, "Adaptive optics scanning laser ophthalmoscope for stabilized retinal imaging ," Optics Express 14 (8) , 3354-3367 (April2006).

Reprinted by permission of the Optical Society of America. For permission to copy or republish, contact the Optical Society of America, 2010 Massachusetts Ave. NW, Washington, DC 20036-1023.

Abstract

A retinal imaging instrument that integrates adaptive optics (AO), scanning laser ophthalmoscopy (SLO), and retinal tracking components was built and tested. The system uses a Hartmann-Shack wave-front sensor and MEMS-based deformable mirror for AO-correction of high-resolution, confocal SLO images. An active retinal tracking with custom processing board senses and corrects eye motion with a bandwidth exceeding 1 kHz. The system includes a wide-field line-scanning laser ophthalmoscope for easy orientation of the high-magnification SLO raster. We demonstrate tracking accuracy down to 6 µm RMS for some subjects (typically performance: 10-15 µm RMS). The system has the potential to become an important tool to clinicians and researchers for vision studies and the early detection and treatment of retinal diseases.

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