Physical Sciences Inc. Publications Abstract: Advanced scanning methods with tracking optical coherence tomography

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Abstract: Advanced scanning methods with tracking optical coherence tomography

Daniel X. Hammer, R. Daniel Ferguson, Nicusor V. Iftimia, Teoman Ustun, "Advanced scanning methods with tracking optical coherence tomography ," Optics Express 13 (20) , 7937-7947 (October2005).

Reprinted by permission of the Optical Society of America. For permission to copy or republish, contact the Optical Society of America, 2010 Massachusetts Ave. NW, Washington, DC 20036-1023.

Abstract

An upgraded optical coherence tomography system with integrated retinal tracker (TOCT) was developed. The upgraded system uses improved components to extend the tracking bandwidth, fully integrates the tracking hardware into the optical head of the clinical OCT system, and operates from a single software platform. The system was able to achieve transverse scan registration with sub-pixel accuracy (~10 µm). We demonstrate several advanced scan sequences with the TOCT, including composite scans averaged (co-added) from multiple B-scans taken consecutively and several hours apart, en face images collected by summing the A-scans of circular, line, and raster scans, and three-dimensional (3D) retinal maps of the fovea and optic disc. The new system achieves highly accurate OCT scan registration yielding composite images with significantly improved spatial resolution, increased signal-to-noise ratio, and reduced speckle while maintaining well-defined boundaries and sharp fine structure compared to single scans. Precise re registration of multiple scans over separate imaging sessions demonstrates TOCT utility for longitudinal studies. En face images and 3D retinal maps generated from these data reveal high fidelity image registration with tracking, despite scan durations of more than one minute.

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