Physical Sciences Inc. Publications Abstract: Tracking Optical Coherence Tomography

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Abstract: Tracking Optical Coherence Tomography

R. Daniel Ferguson, Daniel X. Hammer, Lelia Adelina Paunescu, Siobahn Beaton, Joel S. Schuman, "Tracking Optical Coherence Tomography ," Optics Letters 29 (18) , 2139-2141 (15 September2004).

Reprinted by permission of the Optical Society of America. For permission to copy or republish, contact the Optical Society of America, 2010 Massachusetts Ave. NW, Washington, DC 20036-1023.

Abstract

An experimental tracking optical coherence tomography (OCT) system has been clinically tested. The prototype instrument uses a secondary sensing beam and steering mirrors to compensate for eye motion with a closed-loop bandwidth of 1 kHz and tracking accuracy, to within less than the OCT beam diameter. The retinal tracking improved image registration accuracy to ‹1 transverse pixel (‹60 µm). Composite OCT images averaged over multiple scans and visits show a sharp fine structure limited only by transverse pixel size. As the resolution of clinical OCT systems improves, the capability to reproducibly map complex structures in the living eye at high resolution will lead to improved understanding of disease processes and improved sensitivity and specificity of diagnostic procedures.

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