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Abstract: An Active Retinal Tracker for Clinical Optical Coherence Tomography Systems
Daniel X. Hammer, R. Daniel Ferguson, John C. Magill, Lelia Adelina Paunescu, Siobahn Beaton, Hiroshi Ishikawa, Gadi Wollstein, Joel S. Schuman,
"An Active Retinal Tracker for Clinical Optical Coherence Tomography Systems
,"
Journal of Biomedical Optics
10
(02)
, 1-11
(March2005).
Copyright © 2005 Society of Photo-Optical Instrumentation Engineers.
This paper was published in , Journal of Biomedical Optics
10 and is made available as an electronic reprint (preprint)
with permission of SPIE. One print or electronic copy may be made for personal use only. Systematic or multiple
reproduction, distribution to multiple locations via electronic or other means, duplication of any material in this
paper for a fee or for commercial purposes, or modification of the content of the paper are prohibited.
Abstract
An active, hardware-based retinal tracker was integrated with a clinical optical coherence tomography (OCT) system to investigate the effects of stabilization on acquisition of highresolution retinal sections. The prototype retinal tracker locks onto common fundus features, detects transverse eye motion via changes in feature reflectance, and positions the OCT diagnostic beam to fixed coordinates on the retina with mirrors driven by a feedback control
loop. The system was tested in a full clinical protocol on subjects with normal and glaucomatous eyes. Experimental analysis software was developed to co-align and co-add
multiple fundus and OCT images and to extract quantitative information on location of structures in the images. Tracking was highly accurate and reproducible on all but one subject resulting in the ability to scan the same retinal location continually over long periods of time. The results show qualitative improvement in 97% of co-added OCT scans and a reduction in the variance of the position of the optic disc cup edge to less than one pixel (~60 µm). The tracking system can be easily configured for use in research on ultrahigh-resolution OCT systems for advanced image modalities. For example, tracking will allow full three-dimensional scans of the retina, the duration of which is currently effectively prohibited by eye motion.
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