Hyperspectral Imaging for Process Analytical Technology

Adaptive InfraRed Imaging Spectroradiometry AIRIS™

Research Announcement

• Low-order Fabry-Perot interferometry tunable IR filter*
• Rapid, selective MWIR and LWIR spectral imaging
• High sensitivity from increased IR absorption
• 3-D data cubes (x, y, λ)
• Programmable, rapid tuning to pre-selected wavelengths
• Potential detection of low-concentration, high potency APIs
• Large area imaging covering many dosage units

Potential Applications

• Blend monitoring
• Tablet monitoring
• Cleaning validation

PSI MWIR and LWIR AIRIS Filter

4.66 µm image recorded using AIRIS

PSI is interested in working with pharmaceutical corporate partners to support the development and application of the AIRIS technology for pharmaceutical process analytical technology (PAT).

*W.J. Marinelli, K.W. Holzclaw, S.J. Davis and B.D. Green, "Method and apparatus for imaging," U.S. Patent #5,461,477.

William Kessler Physical Sciences Inc. 20 New England Business Center Andover, MA 01810-1077 Telephone: (978) 689-0003 Fax: (978) 689-3232 kessler@psicorp.com