Smart Multi-grid Template for Focal Therapy of Prostate Cancer

Physical Sciences Inc., in collaboration with the Department of Radiology at Brigham and Women’s Hospital (BWH), has been awarded a research program from the National Institutes of Health (NIH) to develop an automated Smart Multi-grid-guidance Template (SMT) technology that will enable magnetic resonance imaging (MRI)-guided transperineal focal therapy improvement of prostate cancer (PCa).

Focal therapy that targets localized PCa lesions is a growing therapeutic option for PCa patients with unifocal, low- and intermediate-risk cancer. Various energy therapy modalities such as cryoablation, laser ablation, radiofrequency ablation, and high-intensity focused ultrasound have been clinically investigated with regards to improving post-treatment preservation of sexual and urinary function while focally treating PCa. Although these PCa focal therapy modalities have widely been utilized in conjunction with the imaging-guided approaches for precise localization of PCa lesions, accurate placement of the therapy needles within the PCa lesions remains a major challenging problem in improving the PCa therapy success rate. Therefore, PSI is addressing a clinical need for a technology that can provide highly accurate placement of multiple therapy needles onto the targeted PCa lesions during focal therapy.

The central focus of this project is to improve the therapeutic accuracy of MRI-guided transperineal focal treatment in prostate cancer by providing precise therapy needle placement using a Smart Multi-grid Template technology. The device will improve the prostate cancer therapy success rate, reduce the risk of overtreatment for early-stage prostate cancer, and ultimately improve the quality of life for patients and their families.

For more information, contact:

Dr. Nicusor Iftimia
Area Manager, Biomedical Optics Technology
iftimia@psicorp.com
Physical Sciences Inc.
Telephone: (978) 689-0003