Comprehensive Imaging and Quantification of Blood Flow for investigating Ocular Diseases

Physical Sciences Inc. (PSI), in collaboration with New York University (NYU) School of Medicine, has been awarded a research program from the National Institutes of Health (NIH) to develop a novel ophthalmic imaging platform for characterizing retinal morphology and monitoring ocular blood flow abnormalities.

PSI’s platform will combine non-invasive measurements of retina/choroid structure and ocular blood flow based on optical coherence tomography (OCT) and wide-field semi-quantitative global flow visualization using Line-Scanning Doppler Flowmetry (LSDF). The combination of these two imaging modalities within the same imaging platform enables comprehensive assessment of blood flow in the retina and choroid. This novel imaging platform will enable imaging studies in animals and human subjects with normal vision or with various retinal diseases. Prior PSI experience in developing advanced ophthalmic imaging systems coupled with our collaborators’ expertise in Ophthalmology will be leveraged to ensure the successful outcome of this important R&D program.

Degenerative neurovascular diseases of the eye often have either hemodynamic consequences or causes, though the mechanisms are poorly understood. Improved blood flow imaging diagnostics will aid in the detection and management of many eye conditions, and foster new research for understanding the major causes of blindness: age-related macular degeneration, diabetic retinopathy, and glaucoma.

For more information, contact:

Dr. Nick Iftimia
Area Manager, Biomedical Optics Technology
Physical Sciences Inc.
Telephone: (978) 689-0003